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Low-viscosity HPMC also has a lower gelling temperature, making it ideal for use in cold environments Low-viscosity HPMC also has a lower gelling temperature, making it ideal for use in cold environmentshpmc grades and uses.hpmc hydroxypropyl methyl cellulose. As a derivative of cellulose, a natural polymer, HPMC is generally recognized as safe (GRAS) for human consumption by regulatory agencies like the U.S. Food and Drug Administration (FDA). Its safety profile makes it suitable for use in a wide range of products intended for oral intake. The properties of HPMC can be tailored to meet specific needs by varying the degree of substitution and molecular weight. High viscosity grades are often used for their thickening and stabilizing effects in suspensions and emulsions, whereas lower viscosity grades are preferred when a less viscous solution is required. In conclusion, hydroxypropyl methyl cellulose is an essential tool in the pharmaceutical industry. Its multifaceted uses, coupled with its biocompatibility and ease of modification, ensure that HPMC will continue to play a crucial role in the advancement of modern drug delivery systems. As science progresses and new applications emerge, the importance of this cellulose derivative is only set to grow, further cementing its place as an invaluable excipient in the ever-evolving field of pharmaceutics.
The applicant claims that the feed additive HPMC is specified to be manufactured to meet the specifications set for its use as a food additive. The main specifications as food and feed additive are: methoxyl groups ≥ 19 and ≤ 30%, hydroxypropoxyl groups ≥ 3 and ≤ 12%, loss on drying < 10%, sulfated ash < 1.5% (for products with viscosities of 50 mPa.s or above) or < 3% (for products with viscosities below 50 mPa.s). Five batches of the additive were analysed for some of the above specifications, resulting in: methoxyl groups (four batches) 23.5–29.2%, hydroxypropoxyl groups (four batches) 5.2–8.4%, loss on drying (one batch) 1.2% and sulfated ash (one batch) 0.6%. Only statements, without figures, of compliance with the specifications for some impurities (heavy metals, arsenic, solvents, microbial purity) were provided. Information on other impurities ((pesticides, dioxins, dioxin-like and non-dioxin-like polychlorinated biphenyls, mycotoxins, botanical impurities) was not provided.
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Tariffs, trade policies, and exchange rates between countries where HPMC is produced and consumed can significantly affect the import and export costs, impacting the final market price Tariffs, trade policies, and exchange rates between countries where HPMC is produced and consumed can significantly affect the import and export costs, impacting the final market pricehpmc powder price. For example, changes in trade agreements or imposition of anti-dumping duties can lead to a hike in HPMC powder prices.