Home1. Hydroxypropyl Methylcellulose is easily soluble in cold water but difficult to be soluble in hot water. However, its gelling temperature in hot water is significantly higher than that of Methyl Cellulose (MC). And compared with MC, the dissolution in cold water has also been greatly improved.
2)Methyl Cellulose is soluble in cold water, while dissolution in hot water can be challenging. Its aqueous solution is highly stable within a pH range of 3 to 12. It has good compatibility with starch, guar gum, and many surfactants. Gelation occurs when the temperature reaches the gelation temperature.
Hydroxypropyl methyl cellulose (E 464) is identified with the single Chemical Abstracts Service (CAS) number 9004-65-3, and the European Inventory of Existing Chemical Substances (EINECS) number 232-674-9. It is manufactured reacting partially depolymerised cellulose with methyl groups and containing a small degree of hydroxypropyl substitution (Figure 11). Since cellulose is a high molecular weight linear polysaccharide of indeterminate mass and its degree of substitution will depend on the conditions of manufacture, a unique mass and structure cannot be specified. HPMC is in the form of white to off-white powder. A generalised structure of HPMC is shown in Figure 11