hydroxypropyl methyl cellulose cas number

Hydroxypropyl Methylcellulose An Overview

Hydroxypropyl Methylcellulose (HPMC) is a versatile and widely used polymer, primarily known for its applications in the pharmaceutical, food, and construction industries. Its chemical structure allows it to function as a thickener, emulsifier, stabilizer, and film-forming agent, making it an essential ingredient in various products. The CAS number for Hydroxypropyl Methylcellulose is 9004-65-3, which helps in identifying and cataloging this compound in scientific literature and regulatory contexts.

Chemical Structure and Properties

HPMC is derived from cellulose, which is the most abundant organic polymer on Earth. Through a series of chemical modifications, including hydroxypropylation and methylation, cellulose becomes hydroxypropyl methylcellulose. The modifications enhance its solubility in water and improve its thermal gelation properties, which are crucial for its functionality in different applications.

One of the remarkable features of HPMC is its ability to form a gel-like substance upon heating in an aqueous environment. This property is of particular importance in the pharmaceutical industry, where HPMC is used in the formulation of controlled-release drug delivery systems. Its viscosity can be easily adjusted by changing the degree of substitution of hydroxypropyl and methyl groups, allowing for tailored solutions for specific applications.

Applications in Pharmaceuticals

In pharmaceuticals, HPMC serves a multitude of purposes. It is commonly used as a binder in tablet formulations, helping to ensure uniform distribution of powders during production. The polymer's film-forming ability also makes it an ideal coating agent for tablets, providing protection against environmental factors and enhancing the product's aesthetic appeal.

Moreover, HPMC is crucial in ocular formulations, such as eye drops and gels, where it acts as a lubricant and helps maintain moisture on the surface of the eye. Its biocompatibility and non-toxic nature further establish it as a preferred ingredient in various therapeutic applications.

In the food industry, Hydroxypropyl Methylcellulose is used as a dietary thickener and stabilizer. It can improve the texture of food products, making them more appealing to consumers. HPMC is often utilized in gluten-free formulations, where it helps in holding moisture and enhancing the elasticity of doughs and batters, compensating for the absence of gluten. Additionally, its low-caloric nature positions it as an attractive ingredient for health-conscious consumers looking to reduce caloric intake without sacrificing texture or quality.

Use in Construction Materials

Another significant area where HPMC finds application is in construction materials, particularly in cement, mortars, and tile adhesives. It acts as an additive to improve workability, water retention, and adhesion. The presence of HPMC in tile adhesives means that the material doesn't dry out too quickly, allowing for better adjustments during installation and enhancing the final bond strength.

Safety and Regulatory Status

Hydroxypropyl Methylcellulose is generally recognized as safe (GRAS) by the U.S. Food and Drug Administration (FDA) and is permitted for use in both food and pharmaceutical applications. However, as with any chemical, it is essential to follow safety guidelines and regulations to ensure proper handling and usage.

Conclusion

In summary, Hydroxypropyl Methylcellulose (CAS number 9004-65-3) is a multifaceted compound that plays a vital role across various industries. Its unique properties and adaptability make it indispensable in pharmaceuticals, food production, and construction. As research and technology continue to evolve, the versatility of HPMC is likely to expand, leading to new applications and innovations that harness its beneficial properties. Whether improving drug delivery systems, enhancing food textures, or contributing to construction material efficacy, HPMC remains a key player in modern industry.