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hydroxypropyl methyl cellulose cas number

Hydroxypropyl Methylcellulose An Overview

Hydroxypropyl Methylcellulose (HPMC), also known by its CAS number 9004-65-3, is a widely used cellulose ether with numerous applications across various industries. Belonging to the family of modified cellulose polymers, HPMC possesses unique physicochemical properties that make it an ideal candidate for use in food, pharmaceuticals, construction, and personal care products.

Properties and Characteristics

HPMC is water-soluble and biodegradable, making it an environmentally friendly option in many applications. It has excellent film-forming capabilities, high viscosity, and the ability to gel and thicken aqueous solutions. These properties stem from its unique chemical structure, which includes hydroxyl and methoxy groups that enhance its solubility and stability.

One of the defining features of HPMC is its thermal gelation property, which allows it to form gels upon heating, a characteristic that is particularly valuable in cooking and food processing applications. Additionally, its rheological properties can be modified based on the degree of substitution of the hydroxypropyl and methyl groups, which affects the viscosity and gel strength.

Applications

1. Pharmaceuticals In the pharmaceutical industry, HPMC is utilized as a matrix former in controlled-release formulations. Its ability to slow down the release of active ingredients has made it a key component in various tablets, capsules, and other dosage forms. HPMC is also used as a binder for granulation processes and as a coating agent to ensure the integrity and stability of pharmaceutical products.

hydroxypropyl methyl cellulose cas number

2. Food Industry HPMC serves as a food additive, classified under E464, where it is primarily used as a thickener, emulsifier, and stabilizer. It enhances texture and consistency in products such as ice cream, sauces, and dressings. Its foul-tasting properties help in producing low-fat and gluten-free products without sacrificing mouthfeel and viscosity.

3. Construction In construction, HPMC is added to cement-based products, tile adhesives, and waterproofing membranes. It improves workability, enhances adhesion, and prolongs the open time of these products, allowing for easier application. Its water-retention properties are crucial in preventing premature drying, ensuring proper curing and durability of the materials.

4. Cosmetics and Personal Care HPMC is gaining popularity in cosmetics and personal care products, where it serves as a thickening agent and film-former. It is found in formulations such as lotions, creams, and hair styling products, contributing to the aesthetic appeal and functionality. Its ability to stabilize emulsions and enhance the moisture retention of the skin makes it a desirable ingredient in beauty products.

Safety and Regulatory Aspects

HPMC is generally recognized as safe (GRAS) by several regulatory agencies, including the U.S. Food and Drug Administration (FDA). Its non-toxic nature and absence of harmful side effects contribute to its widespread acceptance in consumer products. Nevertheless, it is important to adhere to recommended usage levels as specified by regulatory guidelines.

Conclusion

Hydroxypropyl Methylcellulose is a versatile and valuable compound utilized across a myriad of industries due to its unique properties. As a safe and effective ingredient, HPMC continues to gain traction in innovative applications, particularly as consumers demand more sustainable and high-performance products. From pharmaceuticals to food and personal care, its role in enhancing product quality and performance cannot be overstated. As research progresses, we can expect to see even broader applications and developments surrounding this remarkable cellulose derivative.

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