hydroxypropyl methyl cellulose cas number

Exploring Hydroxypropyl Methyl Cellulose Properties, Applications, and Safety

Hydroxypropyl methyl cellulose (HPMC) is a versatile polymer widely used in various industries due to its unique properties and functionalities. This modified cellulose derivative, known for its emulsifying, thickening, and film-forming abilities, has garnered attention in fields ranging from pharmaceuticals to construction. The Chemical Abstracts Service (CAS) number for HPMC is 9004-65-3, which helps identify its chemical structure and properties accurately.

Properties of Hydroxypropyl Methyl Cellulose

HPMC is synthesized by chemically modifying cellulose, a natural polymer derived from plant cell walls. The structure includes hydroxypropyl and methyl groups, which impart specific characteristics to the compound. One of the key advantages of HPMC is its solubility in water, which can vary based on the degree of substitution of the hydroxypropyl and methyl groups. This tunable solubility allows for its use in applications requiring either a thickening agent or a binder.

Another vital property of HPMC is its stability under varying pH levels and temperatures, making it suitable for a wide range of formulations. Additionally, HPMC does not gel upon heating, which differentiates it from other cellulose derivatives. As a result, it remains consistent in texture, making it ideal for products requiring uniform viscosity and stability.

Moreover, HPMC is known for its rheological properties. It can function as a pseudoplastic material, meaning its viscosity decreases under shear stress. This property is particularly advantageous in applications such as paints and coatings, where ease of application is crucial.

Applications of Hydroxypropyl Methyl Cellulose

1. Pharmaceutical Industry HPMC is extensively utilized as an excipient in drug formulations. Its ability to control the release of active pharmaceutical ingredients (APIs) makes it indispensable in the production of controlled-release tablets and capsules. Furthermore, its film-forming properties allow it to be used as a coating agent for tablets, enhancing their stability and mask taste.

2. Cosmetics and Personal Care In the cosmetics industry, HPMC serves as a thickener, emulsifier, and stabilizer in products such as creams, lotions, gels, and shampoos. Its ability to retain moisture aids in improving the texture and feel of cosmetic formulations while ensuring product stability over shelf life.

3. Construction Industry HPMC plays a significant role in the construction sector as a critical component in tile adhesives, mortars, and plaster. Its water retention properties extend the working time of these products by preventing premature drying. Additionally, it promotes adhesion and improves workability, which is essential for high-quality construction.

4. Food Industry In the food sector, HPMC is considered a safe additive, used primarily as a thickening agent, stabilizer, and emulsifier. It enhances texture and mouthfeel in food products such as sauces and dressings while reducing calorie content in fat-reduced formulations.

Safety and Regulatory Aspects

Hydroxypropyl methyl cellulose is generally recognized as safe (GRAS) by regulatory bodies such as the U.S. Food and Drug Administration (FDA). Its non-toxic nature and inertness make it a preferred choice across various applications. However, manufacturers should adhere to recommended usage levels and guidelines to ensure safety.

Conclusion

Hydroxypropyl methyl cellulose is a multifunctional polymer with broad applicability across multiple industries. Its unique properties, including water solubility, thermal stability, and non-toxic nature, make it an essential ingredient in pharmaceuticals, cosmetics, construction, and food products. As innovation continues in formulation technologies and consumer needs evolve, the demand for HPMC is likely to grow, solidifying its position as an essential material in modern applications. With ongoing research and development, the possibilities for hydroxypropyl methyl cellulose are virtually limitless, paving the way for enhanced product performance and consumer satisfaction.