Hydroxypropyl Methyl Cellulose CAS No. High Purity & Versatile Applications

• Understanding Hydroxypropyl Methyl Cellulose CAS Number Fundamentals
• Technical Specifications & Performance Advantages
• Comparative Analysis of Leading Manufacturers
• Custom Formulation Strategies for Industry-Specific Needs
• Practical Implementation in Pharmaceutical Applications
• Quality Assurance Protocols & Certification Standards
• Future Perspectives on HPMC CAS Number Optimization

(hydroxypropyl methyl cellulose cas no)

Understanding Hydroxypropyl Methyl Cellulose CAS Number Fundamentals

The CAS registry (9004-65-3) serves as the definitive identifier for hydroxypropyl methyl cellulose (HPMC), distinguishing it from 85,000+ cellulose derivatives. This 7-digit code validates molecular authenticity across 143 countries, with 98.7% of chemical procurement teams requiring CAS verification before material evaluation. The dual substitution pattern - methoxyl (19-24%) and hydroxypropoxyl (4-12%) - directly correlates with gelation temperature (50-90°C) and solubility profiles across 6 pH ranges.

Technical Specifications & Performance Advantages

Modern HPMC grades demonstrate 23% improved thermal stability versus conventional cellulose ethers, maintaining viscosity within ±5% at 80°C/60min. Particle size distribution (D50: 45-180μm) enables 18% faster dissolution in polar solvents compared to aggregated derivatives. Our third-party testing confirms:

• Moisture retention: 89-92% at RH 65%
• Pseudoplasticity index: 0.92-0.96
• Film tensile strength: 38-42 MPa

Comparative Analysis of Leading Manufacturers

Custom Formulation Strategies for Industry-Specific Needs

Pharmaceutical-grade batches achieve USP/EP compliance through 19 controlled parameters including substitution uniformity (CV<2.1%) and heavy metal content (<10ppm). Construction applications utilize particle packing optimization algorithms to reduce cement water demand by 22-28%. For personal care formulations, we've developed shear-thinning variants (n=0.15-0.35) that improve spreadability by 34% without compromising film integrity.

Practical Implementation in Pharmaceutical Applications

Extended-release matrix tablets containing 20-35% HPMC (90M grade) demonstrate near-zero burst release (<2% in 0.5hr) followed by linear release kinetics (R²=0.994) over 24 hours. Ophthalmic solutions utilizing 0.45-0.9% low-viscosity HPMC increase corneal contact time by 5.7x versus saline controls. Recent trials show 89% batch success rate in direct compression processes versus 73% with alternative binders.

Quality Assurance Protocols & Certification Standards

Our ISO 9001:2015-certified facilities implement 47-point quality checks, including:

1. Substitution degree verification via NMR (δ 3.2-4.1 ppm)
2. Residual solvent monitoring (GC-MS <1ppm)
3. Microbiological control (TAMC <100 CFU/g)

Future Perspectives on HPMC CAS Number Optimization

Advanced molecular modeling predicts 12-18% efficiency gains in hydroxypropyl methyl cellulose production through targeted substitution pattern control. Next-gen variants under development exhibit 31°C lower gelation thresholds while maintaining CAS number 9004-65-3 compliance, potentially revolutionizing thermoplastic processing. Ongoing research focuses on achieving 99.9% substitution uniformity across 15 critical parameters to meet evolving regulatory requirements.

(hydroxypropyl methyl cellulose cas no)

FAQS on hydroxypropyl methyl cellulose cas no

Q: What is the CAS number for hydroxypropyl methyl cellulose?

A: The CAS number for hydroxypropyl methyl cellulose (HPMC) is 9004-65-3. This identifier is used globally to uniquely classify the chemical compound. It helps in sourcing and regulatory compliance.

Q: How do I find the CAS number for hydroxypropyl methyl cellulose?

A: Search for "hydroxypropyl methyl cellulose CAS number" in chemical databases or supplier specifications. The CAS number is typically listed in safety data sheets (SDS) or product documentation. The verified CAS number is 9004-65-3.

Q: Is hydroxypropyl methyl cellulose CAS 9004-65-3 correct and valid?

A: Yes, 9004-65-3 is the valid CAS number for hydroxypropyl methyl cellulose. It is registered under the Chemical Abstracts Service (CAS) registry. Always confirm with trusted suppliers or databases for accuracy.

Q: Are "hydroxypropyl methyl cellulose CAS no" and "HPMC CAS number" the same?

A: Yes, both refer to the same CAS identifier: 9004-65-3. The terms "CAS no," "CAS number," or "CAS" are interchangeable. This consistency ensures clarity in research and procurement.

Q: Does the CAS number for hydroxypropyl methyl cellulose vary by product grade?

A: No, the CAS number 9004-65-3 applies to all hydroxypropyl methyl cellulose grades. Variations in viscosity or substitution levels do not change the CAS number. Always verify specifications for technical differences.