Hydroxypropyl Methylcellulose (HPMC) is a versatile and widely used polymer in the pharmaceutical industry. It is primarily utilized as a binder, disintegrant, and film-forming agent in the production of tablets.
As a binder, HPMC helps to hold the tablet together by forming strong bonds between the powdered ingredients. This is particularly important for maintaining the structural integrity of the tablet during handling and transportation. In addition, HPMC also helps to control the rate at which the tablet dissolves in the gastrointestinal tract, which can be crucial for delivering the desired therapeutic effect.
As a disintegrant, HPMC accelerates the breakdown of the tablet into smaller particles when it comes into contact with moisture. This is essential for ensuring that the active ingredient is released quickly and effectively once the tablet reaches the stomach. HPMC is particularly effective at promoting disintegration in tablets containing drugs that are sensitive to moisture or heat HPMC is particularly effective at promoting disintegration in tablets containing drugs that are sensitive to moisture or heat

HPMC is particularly effective at promoting disintegration in tablets containing drugs that are sensitive to moisture or heat HPMC is particularly effective at promoting disintegration in tablets containing drugs that are sensitive to moisture or heat
hydroxypropyl methylcellulose uses in tablets.
Finally, HPMC is also used as a film-forming agent in the production of enteric coated tablets. These tablets are designed to release the active ingredient in the intestine rather than the stomach, which can help to protect the drug from degradation or irritation in the stomach. HPMC forms a protective coating around the tablet that is resistant to stomach acid, allowing it to pass through the stomach undamaged and then dissolve in the intestine.
Overall, the versatility and effectiveness of HPMC make it an indispensable tool for manufacturers of solid dosage forms. Its ability to perform multiple functions in the tablet manufacturing process makes it a popular choice among pharmaceutical companies around the world.