hydroxypropyl methyl cellulose cas no

Hydroxypropyl Methyl Cellulose (HPMC) An Overview

Hydroxypropyl Methyl Cellulose (HPMC) is a versatile and widely used cellulose derivative that has found applications across various industries, including pharmaceuticals, food, cosmetics, and construction. It is a semi-synthetic polymer that is not derived from natural sources but is synthesized through the chemical modification of cellulose, making it resistant to biodegradation. The CAS number for HPMC is 9004-65-3.

The chemical structure of HPMC comprises a cellulose backbone that has been chemically modified to include hydroxypropyl and methyl groups. This modification significantly enhances the solubility and applicability of cellulose, allowing HPMC to dissolve in cold water and create gel-like solutions. As a result, HPMC is often utilized as a thickening agent, emulsifier, and stabilizer in various formulations.

In the pharmaceutical industry, HPMC plays a crucial role as a binder in tablet formulations, ensuring uniform distribution of active ingredients. This characteristic helps enhance the bioavailability of drugs by controlling the release profile, allowing for sustained or extended-release formulations. Moreover, HPMC is commonly used as a film-forming agent in coatings for tablets and capsules, providing moisture protection and improving the overall aesthetic appearance of these dosage forms.

HPMC is also approved as an excipient by regulatory authorities, such as the Food and Drug Administration (FDA), for use in drug manufacturing. Its non-toxic nature and ability to form viscous solutions make it a preferred choice in the formulation of various pharmaceutical products, including eye drops and gels.

Role in Food Technology

In the food industry, HPMC serves as a thickening and stabilizing agent, enhancing the texture and mouthfeel of food products. It improves the consistency of sauces, dressings, and dairy products by preventing the separation of ingredients and enhancing the overall quality of the food. Additionally, HPMC is used in gluten-free baking to improve dough consistency and aid in moisture retention, which is especially beneficial for individuals with gluten sensitivities.

Moreover, HPMC is recognized for its emulsifying properties, allowing it to stabilize oil-water mixtures in products like mayonnaise and salad dressings. Its ability to form gels and foams has also spurred its use in low-fat and reduced-calorie foods, where it can help mimic the textures typically associated with higher-fat products without adding significant calories.

HPMC in Cosmetics and Personal Care

HPMC is a popular ingredient in the cosmetics and personal care sector due to its emulsifying, thickening, and film-forming properties. It is commonly found in skincare products, shampoos, and conditioners, where it helps improve the texture and spreadability of formulations. HPMC can also provide a smooth and velvety finish in makeup products, contributing to a more pleasant user experience.

Additionally, HPMC offers moisture retention capabilities, making it an excellent choice for moisturizing creams and lotions. Its safe and non-irritating nature makes it suitable for sensitive skin formulations, adding to its appeal in the beauty market.

Construction and Building Materials

In construction, HPMC is used as an additive in cement-based products such as tile adhesives, plasters, and mortars. Its incorporation helps improve workability, adhesion, and water retention of these materials. The thickening properties of HPMC also enhance the stability of these products, preventing sagging and improving the overall performance during application.

Conclusion

Hydroxypropyl Methyl Cellulose (HPMC) stands out as a multifunctional ingredient with a broad range of applications, particularly in pharmaceuticals, food technology, cosmetics, and construction. Its unique chemical properties provide various benefits, improving product performance and enhancing consumer experiences. As industries continue to innovate and look for effective solutions, the relevance of HPMC is expected to grow, ensuring its place as a key ingredient in many formulations. Its safety, efficacy, and versatility make it a valuable asset in the toolkit of formulators across diverse sectors.