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HYDROCEL – HPMC/HYPROMELLOSE

Hypromellose also known as HPMC is a cellulose ether derivative. Hydroxypropyl methylcellulose (HPMC) or hypromellose can be used as a thickening agent, binder, film former, and hydrophilic matrix material.

Hydroxypropyl Methylcellulose (HPMC) plays a crucial role in pharmaceutical formulations due to its diverse range of benefits. One of its primary uses is as a key component in controlled-release drug delivery systems. HPMC’s ability to modify drug release rates enables pharmaceutical companies to develop medications that provide sustained therapeutic effects, leading to improved patient compliance and reduced dosing frequency. Moreover, HPMC is utilized as a binder in tablet formulations, contributing to the mechanical strength and disintegration properties of tablets, thereby ensuring consistent drug release and bioavailability. Its biocompatibility and inert nature make it suitable for a wide range of drug formulations, including oral, topical, and ophthalmic products, underscoring its versatility in pharmaceutical applications.

HPMC

The benefits of incorporating HPMC into pharmaceutical formulations are manifold. By utilizing HPMC as a matrix former in sustained-release dosage forms, pharmaceutical manufacturers can achieve precise control over drug release, leading to optimized therapeutic outcomes and minimized side effects. Furthermore, HPMC’s bioadhesive properties make it suitable for use in ophthalmic formulations, enhancing the contact time of drugs with ocular tissues and improving the efficacy of treatments for conditions such as glaucoma and dry eye syndrome. Additionally, HPMC’s compatibility with a variety of active pharmaceutical ingredients and its ability to enhance solubility and bioavailability further contribute to its value in pharmaceutical applications, making it a preferred choice for formulators seeking to develop safe, effective, and patient-friendly drug products.

The hydrophilic matrix system is the simplest sustained release technology for oral dosage forms, consisting essentially of a drug and a water soluble, highly viscous polymer. It does not require any other excipient. Hydrocel range of HPMC is a “tailored to perform” range of cellulose ethers having their specifications in line with multiple pharmacopoeia while keeping the results in a narrow range to ensure consistency in batch to batch results is achieved every time. With narrow parameter range Hydrocel range of Cellulose & Polymers are available in different grades to support various different application. They have gained excellent feedback from the customers and have excellent performance results. HPMC also gives excellent finish for tablet and pellet coatings.

What is Hydroxypropyl Methylcellulose Used For?